If the moon has valuable resources then it's worth going, but otherwise it's not much better than LEO. We need to be striving for the asteroid belt, and perhaps Mars, and the moon doesn't much help us there, again, unless there's resources there.
Hopefully the James Webb Space Telescope will be a good first step towards pushing our infrastructure out more, along with the Space Launch System that NASA and the White House have agreed to replace Constellation with.
On the subject of nuclear fusion, ITER has potential on really, really big scales, but tokamak reactors are just grossly wasteful. The most promising fusion initiative, in my opinion, is Polywell, which, by design, suffers far fewer electron losses and is apparently net-power capable. EMC2, under their contract with the US Navy, expects to have a production fusion reactor up by the end of the decade (and technically, they're ahead of schedule on that roadmap, last I heard).
As for Andrea Rossi's ECAT device, I'm sorry to say that as much as I'd like cold fusion, the reason the world isn't jumping on buying these things is because they're a scam. Rossi has never submitted one of these devices for independent testing, and when that is eventually done, I doubt anything substantiating will be found, because when demonstrations have been held for the device, proper science was often ignored and the device did not behave in a way that corroborated Rossi, and Rossi has made many claims that he could easily verify to show that these devices work (which you'd obviously do since they're a commercial product), but has refused that verification, for instance claiming an ECAT heats a factory in Bondeno, Italy, but refusing to show it to anyone.
http://www.physorg.c...lity-video.html
Thus far, my money's on Polywell, as the little snippets we've gotten sound very promising (though, sadly, they're under a USN information embargo), and it sounds like scaling it working in their favor, with a good chance of net power generation. If the Navy suddenly and inexplicably drops the project, I guess we'll know it's it's a bust, but until then, I'm hopeful