My lrm boat Jager I use all 5 mouse buttons
Left mouse - AC/2
Right mouse - tag
Mouse wheel button - 2 lrm 5's on chain fire (used for shots that mostly will miss, annoyance factor, or to determine enemy position via their ams)
Button 4 - dual lrm 15's together
Button 5 - Med laser for when I'm out of ammo
In most other mechs, I use left mouse button for weapons mounted on the left side of the mech, right mouse button for weapons mounted on the right side of the mech. This allows me to edge out a little past cover and fire only the weapons that have clear Los.
Edited by Dracol, 06 July 2013 - 03:41 PM.