Stalker 5S
Large Pulse Laser Range 7.5%
Energy Range 7.5%
Medium Laser Duration -7.5%
Laser Duration -7.5%
Missile Heat Gen -10%
I've enjoyed running the 5S against Clan mechs, because it has dual AMS. Couple with this the incoming laser changes in the November roadmap and you may have a case for a viable and survivable LPL Stalker!

So, even with the LPL duration being increased to from 0.6 to 0.67 in the NOV4 patch, with Range and Cooldown level 5's slotted in, and the quirk changes above, you'd have quad LPL with:
Duration (quirk): 0.67*(1-0.075) = 0.619s
Range (module+quirk): 365*(1+0.125+0.075+0.075) = 465.3m
Cooldown (module): 3.25*0.875 = 2.84s
Just tinkering in Smurfy, you can fit in Quad LPL, 20DHS, and DUAL AMS (AMS ammo is being doubled on Nov4). Uses endo though, for the STD300. If you take out endo, you can fit in a 275 and one extra heatsink. You'd have to stagger the alpha to avoid the lurking threat of ghost heat, but if you use fire discipline and stagger each arm between the 2.84 seconds you'd have a 22DMG 0.62s duration 14 heat laser alpha every 1.4 to 1.5 seconds. Chain fire it for DakkaWub! Mind you, the 5S has less than stellar torso twist, but if you aren't brawling in the thick of it, it shouldn't be an issue.
Also, looking at the MLAS changes:
Duration (quirk): 0.9*(1-(0.075*2))= 0.765s!!!
Range (module): 405*1.125 = 455m
Cooldown (module): 3*0.875 = 2.625s
Smurfy to the rescue again, for a laser vomit build:
Running 2 LPL + 4 MLAS, and you have very similar range, cooldown and duration between the LPL and MLAS for a 30 heat, 42DMG ghost heat free alpha strike. Also, with the free space, you could add a couple of -10% heat troll LRM5's for panic inducing goodness! Or screw the MLAS and LRM's and go FULL WUB.
Mind you, if you use MLAS and LPL, you can't fit in all the modules, but this might be the first case where I actually use the mech/weapon slot for an actual weapon module.
Using Dual AMS and the insanely hard to kill-ness of the Stalker, (though it would still have to be wary of it's main predator, the DakkaWhale) could we see a semi viable BrawlStalker?
Have you guys seen anything in the quirklist that excites you?