![Posted Image](https://secure.logitech.com/assets/17670/17670.png)
Left mouse fires group 1 (usually left arm weapons)
Right mouse fires group 2 (usually right arm weapons)
Back thumb (mouse 4) fires group 3 (usually torso-mounted MLs, SRMs, or group-fired LRMs if I have LRMs)
Front thumb (mouse 5) fires group 4 (chain-fired LRMs if I have LRMs, or another group of MLs/SRMs)
Mouse wheel click zooms.
That's my setup, and it suits me fine. Having left-side weapons on left mouse and right-side weapons on right makes it easier for me to not shoot cover when I hug corners, and also makes it easier to manage heat.
Having LRMs split on two buttons for group- or chain-fire also makes it easy to choose if you want to rattle the target or saturate his AMS with a big salvo.
If I want to alpha I press all buttons, the thumb can easily press both thumb buttons at once.
Only time it gets hairy is when the 'mech has more than four weapon groups - but then I probably need to revisit that build anyway
![;)](https://static.mwomercs.com/forums/public/style_emoticons/default/wink.png)